PepS: An Innovative Microfluidic Device for Bedside Whole Blood Processing before Plasma Proteomics Analyses.
Gilquin B, Cubizolles M, Den Dulk R, Revol-Cavalier F, Alessio M, Goujon CE, Echampard C, Arrizabalaga G, Adrait A, Louwagie M, Laurent P, Navarro FP, Couté Y, Cosnier ML, Brun V.
Gilquin B, et al.
Anal Chem. 2021 Jan 19;93(2):683-690. doi: 10.1021/acs.analchem.0c02270. Epub 2020 Dec 15.
Anal Chem. 2021.
PMID: 33319979
In less than 2 h, the PepS device allows bedside plasma separation from whole blood, volume metering, depletion of albumin, protein digestion with trypsin, and stabilization of tryptic peptides on solid-phase extraction sorbent. ...
In less than 2 h, the PepS device allows bedside plasma separation from whole blood, volume metering, depletion of albumin, protein d …